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Peptide

GB-115

Also called GB115

Overview

No reference-database description is on file for this compound yet.

What studies say

Sentences quoted word for word from open-access (CC BY) journal articles. They describe research findings, not dosing advice.

“The pilot clinical study of GB-115, a new peptide antagonist of central cholecystokinin-1 receptors, revealed that drug was clinically effective in patients with generalized anxiety disorder (GAD [generalized anxiety disorder[1]]) at dose 6 mg daily.”[1] (Dorofeeva O et al., European psychiatry : the journal of the Association of European Psychiatrists, 2022, abstract)

“The impact of a new peptide antagonist of central cholecystokinin-1 receptors (GB-115) on cognitive processes in patients with GAD [generalized anxiety disorder[2]] is reported.”[2] (Dorofeeva O et al., European psychiatry : the journal of the Association of European Psychiatrists, 2022, abstract)

Chemistry

Formula
C25H30N4O3 PC
CAS number
678996-63-9 PC
Molar mass (g/mol)
434.5 PC
IUPAC name (computed by PubChem)
N-[2-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]-6-phenylhexanamide PC
SMILES
C1=CC=C(C=C1)CCCCCC(=O)NCC(=O)N[C@@H](CC2=CNC3=CC=CC=C32)C(=O)N PC
InChIKey
ZBIQNIJICMOVKN-QFIPXVFZSA-N PC
PubChem CID
11281948

Abbreviations

GAD
generalized anxiety disorder [1]
GAD
generalized anxiety disorder [2]

Harm reduction information

No harm reduction data is on file for this compound yet. That means no dose, timing or combination data from PsychonautWiki or TripSit. Please don't guess a dose from similar compounds. If you have taken it and feel unwell, contact emergency services or a poison control center.

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User reports

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Pop culture

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Sources

  1. Journal / agency Dorofeeva O, Syunyakov T, Metlina M, Ivashkina N. Clinical effects of central antagonist of cholecystokinin-1 receptors GB-115 in patients with Generalized Anxiety Disorder. European psychiatry : the journal of the Association of European Psychiatrists. 2022. · PMC9564032 · Open access, CC BY licence; quoted word for word
  2. Journal / agency Dorofeeva O, Metlina M, Chepeliuk A, Vinogradova M. Impact of central antagonist of cholecystokinin-1 receptors GB-115 on cognitive functions in patients with Generalized Anxiety Disorder. European psychiatry : the journal of the Association of European Psychiatrists. 2022. · PMC9563656 · Open access, CC BY licence; quoted word for word
  3. Journal / agency PubChem (U.S. National Library of Medicine). Compound summary, CID 11281948. Retrieved 10 November 2026. Formula, mass, names and identifiers in the Chemistry table