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Blue Lotus

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Dosage

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Duration

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Mixing

Acute combinations: what happens when these are taken close together. Entries backed by a medical journal or agency are listed first.

Backed by medical journals

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Risks and toxicity

The toxicity of Blue Lotus is misunderstood and poorly researched. Only the pure alkaloids have been tested with little toxicity, however, mixing Blue Lotus with other substances could present a risk. PW

It is strongly recommended that one use harm reduction practices when using this substance. PW

Lethal dosage

There are no studies on aporphine in animals. However, studies on subcutaneous apomorphine injection, the bioactive form of aporphine, have been carried out. In a 5-day study, mice were administered up to 10 mg/kg apomorphine subcutaneously daily. No adverse effects were observed other than a slight increase in dopamine levels. PW

Tolerance and addiction potential

Blue Lotus is not thought to be addictive. Its compounds have been used in the treatment of alcohol and morphine addiction. PW

Dangerous interactions

The main and absolute contraindication to using Blue Lotus, is the concurrent use of adrenergic receptor antagonists; combined, they cause a severe drop in blood pressure and fainting. PW

L-DOPA and Blue Lotus could pose risks and cause symptoms such as sleepiness, dizziness, runny nose, sweating and tremors. PW

Testing

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Effects

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Overview

Nymphaea nouchali var. caerulea (Commonly known as Blue Lotus) is a water lily found throughout most of the eastern half of Africa. PW

Nymphaea nouchali var. caerulea, or simply Nymphaea caerulea, also known as blue lotus or blue water lily among many other names, is a water lily in the genus Nymphaea, a botanical variety of Nymphaea nouchali.[1–9] WP⚠ The source has a footnote here that is not shown.

It is an aquatic plant of freshwater lakes, pools and rivers, naturally found throughout most of the eastern half of Africa, as well as parts of southern Arabia, but has also been spread to other regions as an ornamental plant. It can tolerate the roots being in anoxic mud in nutritionally poor conditions, and can become a dominant plant in deeper water in such habitats. The underwater rhizomes are edible. WP

It features prominently in Egyptian mythology and art, symbolizing the sun and rebirth and has been found in pharaohs' tombs. It may have been used for aphrodisiac and religious purposes, including in rituals like Hathor's Festival of Drunkenness. The plant contains the psychoactive alkaloids nuciferine and apomorphine, which interact with the serotonin, dopamine, and adrenergic systems. Modern recreational use, primarily through drinking infusions or vaping, has been associated with toxicity, causing symptoms like sedation and perceptual disturbances. Recent research by UC Berkeley confirmed that the authentic Nymphaea caerulea is chemically distinct from many products sold online, which contain significantly less of the alkaloid nuciferine and are misidentified water lilies.[10][11] WP

Nymphaea caerulea, first described by Marie Jules César Savigny in 1798, was later classified as a variety of Nymphaea nouchali by Bernard Verdcourt in 1989. Though it is still most commonly referred to as a variety of Nymphaea nouchali, recent phylogenetic studies have problematized the taxonomy. When defined taxonomically as Nymphaea nouchali var. caerulea, it is considered synonymous with Nymphaea capensis. When considered taxonomically as Nymphaea caerulea, it is now rare due to habitat loss from the Aswan Dam.[4] WP

History

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Pharmacology

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Chemistry

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User reports

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Listings
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Pop culture

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References

  1. Other Nymphaea nouchali var. caerulea (Savigny) Verdc. March 2017
  2. Other GRIN
  3. Other Nymphaea caerulea
  4. Other Viljoen, Cherise; Notten, Alice. Nymphaea nouchali var. caerulea. January 2002
  5. Other Cholo, F.; Foden, W. Blue Waterlily. 22 May 2006
  6. Other Nymphaea caerulea
  7. Other Wiersema, John H. Flora of North America: North of Mexico. 21 August 1997
  8. Other Nymphaea capensis Thunb. 2011
  9. Other Wunderlin, Richard P.; Hansen, Bruce F.; Franck, Alan R.; Essig, F. B. Nymphaea capensis var. zanzibariensis. 30 March 2021
  10. Journal / agency Schimpf, Mackenzie; Ulmer, Thomas; Hiller, Hugh; Barbuto, Alexander F. Toxicity From Blue Lotus (Nymphaea caerulea) After Ingestion or Inhalation: A Case Series. Military Medicine. 22 July 2023. doi:10.1093/milmed/usab328 · PMID 34345890
  11. Other Pohl, Jason. Investigating the psychedelic blue lotus of Egypt, where ancient magic meets modern science. 11 March 2025
  12. Other Kesselring, Jason R. INFORMATION PAPER. 2021-12-09
  13. Other Blue lotus: Prohibited for use. 2024-04-22
  14. Other 86th Airlift Wing Public Affairs. BLUF: Blue Lotus Undermines your Future. 2024-11-12
  15. Other Army CID Europe Field Office. Blue Lotus Products. 2025-05-09
  16. Other Par Krimināllikuma spēkā stāšanās un piemērošanas kārtību
  17. Other Dz.U. 2009 nr 63 poz. 520, Internetowy System Aktów Prawnych in lang pl
  18. Other Постановление Правительства Российской Федерации от 31 декабря 2009 г. № 1186. 2009

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