Acipimox
Overview
NCI Thesaurus: Acipimox is a niacin derivative and nicotinic acid analog with activity as a hypolipidemic agent. Acipimox has special application for the treatment of hyperlipidemia in non-insulin-dependent diabetic patients.[1] PC
What studies say
Sentences quoted word for word from open-access (CC BY) journal articles. They describe research findings, not dosing advice.
“Acipimox is a licensed lipid-lowering agent known to act as an NAD [nicotinamide adenine dinucleotide[3]] precursor.”[3] (McDonald C et al., BMJ open, 2024, abstract)
Chemistry
Abbreviations
- NAD
- nicotinamide adenine dinucleotide [3]
Harm reduction information
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Sources
- Journal / agency NCI Thesaurus (U.S. National Cancer Institute). Description text for Acipimox, as shown in the PubChem record (CID 5310993), retrieved 10 November 2026. Licence: Free of copyright, credit NCI; quoted word for word
- Journal / agency MeSH (Medical Subject Headings, U.S. National Library of Medicine). Description text for Acipimox, as shown in the PubChem record (CID 5310993), retrieved 10 November 2026. Licence: Public domain (U.S. government work); quoted word for word
- Journal / agency McDonald C, Alderson C, Birkbeck MG, Brown L, Del Din S, Gorman GG, Hollingsworth K, Massarella C, Rehman R, Rochester L, Sayer AA, Su H, Tuppen H, Warren C, Witham MD. A study protocol to investigate if acipimox improves muscle function and sarcopenia: an open-label, uncontrolled, before-and-after experimental medicine feasibility study in community-dwelling older adults. BMJ open. 2024. doi:10.1136/bmjopen-2023-076518 · PMID 38417968 · PMC10900389 · Open access, CC BY licence; quoted word for word
- Journal / agency PubChem (U.S. National Library of Medicine). Compound summary, CID 5310993. Retrieved 10 November 2026. Formula, mass, names and identifiers in the Chemistry table