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Serotonergic psychedelic · Hallucinogen

1SB-LSD

Original Wikipedia articleen.wikipedia.org/wiki/1SB-LSD revision used (24 October 2026)

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Overview

1SB-LSD, or 1BS-LSD, also known as 1-TMSBz-LSD or as 1-(4-(trimethylsilyl)benzoyl)-LSD, is a psychedelic drug of the lysergamide family related to lysergic acid diethylamide (LSD). It is thought to be a prodrug of LSD. The drug was encountered online as a novel designer drug in September 2025. 1SB-LSD has been sold in the form of blotter, for instance containing 165 μg per tab. It is the derivative of 1Bz-LSD (SYN-L-018) in which there is a 4-trimethylsilyl group on the benzyl ring. 1SB-LSD was first described in the scientific literature by 2026. It is not an explicitly controlled substance in the United States or in Canada.[1–5] WP

Drug class

Serotonergic psychedelic Hallucinogen WP

From the Wikipedia article's infobox.

Chemistry

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Harm reduction information

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Sources

  1. Other 1BS-LSD
  2. Journal / agency Tanaka R, Kawamura M, Ito M, Kikura-Hanajiri R. Identification and Analysis of Lysergic Acid Diethylamide Analogs, 4-Benzoyl-N,N-Diethyl-7-Methyl-4,6,6a,7,8,9-Hexahydroindolo[4,3-fg]quinoline-9-Carboxamide (1Bz-LSD) and N,N-Diethyl-7-Methyl-4-(4-(Trimethylsilyl)Benzoyl)-4,6,6a,7,8,9-Hexahydroindolo[4,3-fg]quinoline-9-Carboxamide (1-TMSBz-LSD), in tablet or paper sheet products available online in Japan. Drug Test Anal. April 2026. doi:10.1002/dta.70039 · PMID 41709646
  3. Other Prodrugs of Substituted Ergolines
  4. Other Orange Book: List of Controlled Substances and Regulated Chemicals (January 2026). January 2026
  5. Other Controlled Drugs and Substances Act. 5 December 2025

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