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RX Graveyard · by country

RX Graveyard: United States

12 of the 16 RX Graveyard substances, in order of the date the United States regulated them.

Each line restates what the linked source says, with its date. Some sources give only a month or a year. Laws change, so check current rules.

RegulatedSubstanceWhat the law did
1984MethaqualoneSedative-hypnoticMoved to Schedule I, after being withdrawn from the market in 1983.[1]
2002BenzylpiperazineStimulantFederally classified as a Schedule I controlled substance.[2]
1 March 2011JWH-018Synthetic cannabinoidTemporarily scheduled by 76 FR 11075.[3]
October 2011MephedroneStimulant (cathinone)Temporarily classified as Schedule I (announced September 2011).[4]
21 October 2011MDPVStimulant (cathinone)DEA issued a temporary one-year ban, classifying it as Schedule I.[5]
15 November 201325I-NBOMePsychedelicDEA added it to Schedule I using emergency scheduling powers, for 2 years.[6]
27 February 2014α-PVPStimulant (cathinone)Temporary Schedule I ban, with nine other synthetic cathinones.[7]
16 May 2016AH-7921OpioidPlaced in Schedule I of the Controlled Substances Act.[8]
14 November 2016U-47700OpioidPlaced in Schedule I of the Controlled Substances Act.[9]
6 June 2022MethoxetamineDissociativeDEA published a final rule placing MXE in Schedule I.[10]
21 November 2024EthylphenidateStimulantPlaced in Schedule I of the Controlled Substances Act.[11]
21 September 2026DiphenidineDissociativeDEA final rule placed it in Schedule I.[12]

Sources

  1. Wikipedia, "Methaqualone"
  2. Wikipedia, "Benzylpiperazine"
  3. Wikipedia, "JWH-018"
  4. Wikipedia, "Mephedrone"
  5. Wikipedia, "Methylenedioxypyrovalerone"
  6. Wikipedia, "25I-NBOMe"
  7. Wikipedia, "Α-Pyrrolidinopentiophenone"
  8. Wikipedia, "AH-7921"
  9. Wikipedia, "U-47700"
  10. Wikipedia, "Methoxetamine"
  11. Wikipedia, "Ethylphenidate"
  12. DEA, "Schedules of Controlled Substances: Placement of Diphenidine in Schedule I", final rule, FR Doc. 2026-19231 (21 September 2026)

Other countries (OECD members, A to Z)