Mixing

Combination chart

Combination data from TripSit (tripsit.me). Their full chart, with explanations, is at combo.tripsit.me. Tap any cell for TripSit's rating and sources for that pairing. TripSit's own note for each pairing is on combo.tripsit.me.

From TripSit's chart: "This chart is meant as a quick reference guide and additional research must always be done." Data read 2026-10-24 from TripSit's combos.json (repository); snapshot SHA-256 c655095058771037….

Low Risk & SynergyLow Risk & No SynergyLow Risk & DecreaseCautionUnsafeDangerousNo rating

A colour is not a dose. "Low risk" is TripSit's rating of a pairing, not a statement about any amount, any body, or anything else you have taken. Each substance's page carries the journal-backed interactions and the sources behind them.

	Mescaline	NBOMes	2C-x	2C-T-x	5-MeO-xxT	Cannabis	Ketamine	MXE	Nitrous	Amphetamines	MDMA	Cocaine	Caffeine	Alcohol	GHB/GBL	Opioids	Benzodiazepines	MAOIs	SSRIs	AMT	DPH	Lithium	Mephedrone	PCP	Pregabalin
LSD
Mushrooms
DMT
Mescaline																							no rating
DOx
NBOMes																							no rating
2C-x																					no rating		no rating
2C-T-x																					no rating		no rating		no rating
5-MeO-xxT																					no rating	no rating	no rating
Cannabis																					no rating	no rating	no rating
Ketamine																							no rating
MXE																							no rating
DXM
Nitrous																					no rating		no rating
Amphetamines																							no rating
MDMA																					no rating
Cocaine																							no rating
Caffeine																						no rating
Alcohol																						no rating	no rating		no rating
GHB/GBL																						no rating
Opioids																						no rating
Tramadol
Benzodiazepines																						no rating	no rating		no rating
MAOIs																						no rating	no rating		no rating
SSRIs																							no rating		no rating
AMT																					no rating	no rating	no rating		no rating
DPH			no rating	no rating	no rating	no rating			no rating		no rating									no rating				no rating
Lithium					no rating	no rating							no rating	no rating	no rating	no rating	no rating	no rating		no rating			no rating	no rating	no rating
Mephedrone	no rating	no rating	no rating	no rating	no rating	no rating	no rating	no rating	no rating	no rating		no rating		no rating			no rating	no rating	no rating	no rating		no rating		no rating
PCP																					no rating	no rating	no rating		no rating
Pregabalin				no rating										no rating			no rating	no rating	no rating	no rating		no rating		no rating

Credit

Combination data from TripSit (tripsit.me). Their full chart, with explanations, is at combo.tripsit.me. Links: https://combo.tripsit.me · https://github.com/TripSit/drugs. No licence is stated for TripSit's drug data. We show only their ratings and source links, credited to TripSit; their notes stay on their site.